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STOP! -Before You Take That Next Diet Pill

Wendy Gesaman
Doctor of Pharmacy Candidate, 2001
Ohio Northern University

It seems that everyone wants to lose weight. Today you can find weight loss products in pharmacies, grocery stores, and even at the mall. But are these products safe? A 42-year old mother bought an herbal weight loss product that contained the herb ephedra. She thought the herbal diet aid "had to be" safe because the label said it was "all natural". After taking the weight loss product for 8 days, she started to complain of a headache and a tight feeling in her chest. Later that day, she was rushed to the emergency room because her heart stopped beating and she stopped breathing. She spent the next ten days on life support. This woman was lucky, she survived.

Herbal diet aids and over-the-counter (OTC) diet aids are sold across the United States without a prescription. Ephedra, also known as ma huang, has been used by the Chinese for more than 5000 years. Today ephedra continues to find its place in the herbal market as a weight loss product. The New England Journal of Medicine (NEJM) released an article regarding the risks of phenylpropanolamine (PPA), which is another diet aid similar in many ways to ephedra. The article concluded that women who take PPA products may be at a greater risk for developing a type of stroke in which blood leaks into the brain. Even though the risk of having a stroke is rare, the Food and Drug Administration (FDA) has asked the companies that produce drug products containing PPA to voluntarily stop selling these products. While consumers will no longer be able to buy OTC products that contain PPA, they can still buy herbal weight loss products that contain forms of ephedra. In fact, the American Herbal Products Association (AHPA) estimated that over 3 billion doses of ephedra products were sold last year. Popular herbal diet products that contain ephedra include: Diet Fuel® (Twin Laboratories), ThermiCare® (Met-Rx USA) ETA Stack® (Nutra Sport), Xenadrine RFA-1® (Cytodyne Technologies) and Metabolife 356® (Metabolife International). These products are easy to buy, but how safe are they?

Ephedra has been linked to serious side effects such as death, strokes, and seizures. So why did the FDA ask that PPA be removed from the market and leave ephedra on the market? Since ephedra is classified as an herbal dietary product, it doesn't have to meet the same safety standards as prescription and OTC drugs.

The message to every consumer is: Before you start taking an ephedra diet aid be sure it is safe for you to use. Where do you get good advice on herbal weight loss products? That can be a challenge.

One night after work another Doctor of Pharmacy student and I went into a major chain store that sells herbal products and vitamins. I asked the salesman to show me where the weight loss products were and if any of them contained ephedra. He not only showed me the weight loss products that contain ephedra, but recommended that I buy one of them. This surprised me because neither my friend nor I need to lose weight. Ephedra products definitely are linked to serious risks, but no one asked me any of the following questions:

  • Do you have a heart condition or an irregular heart beat?
  • Do you have liver problems, diabetes, high blood pressure, or thyroid problems?
  • Do you get a lot of headaches?
  • Have you ever had a stroke (bleed in the brain) or a seizure?
  • Are you depressed or taking a medicine to treat depression?
  • Are you nervous or anxious?
  • Are you pregnant or nursing a child?

If you answered " yes" to any of the above questions, ephedra is probably not safe for you.

More research needs to be done on herbal weight loss products. If you take an herbal supplement and develop an unwanted effect, report it to the FDA's MedWatch program at 1-800-332-1088. By calling this number you can help protect the public from harmful side effects.

As a consumer it is important to check the labels of weight loss products. There are herbal weight loss products available that do not contain ephedra. However, if you want to lose weight, a trip to the doctor's office is the safest place to start. Old-fashioned exercise and a healthy diet may still be your best option to shed those extra pounds. You can also ask your doctor or pharmacist about prescription medicines available for weight loss. Remember, just because a product is "natural" doesn't mean it is safe. You are the only one who can decide if you are willing to take the risk of using a herbal product.

© 2001 Consumer Health Information Corporation. All rights reserved.